MotilPro is an advanced gut signaling support formula, supporting serotonergic and cholinergic function for healthy gut motility.Proper gastrointestinal motility is essential for optimal rates of nutrient and fluid absorption, elimination of toxins and overall abdominal comfort. GI motility is regulated by over 100 million neurons embedded in the walls of the GI tract. Collectively known as the enteric nervous system, or the “gut brain,” these neurons communicate by way of numerous neurotransmitters and neurohormones to coordinate smooth muscle contraction.MotilPro supports serotonergic and cholinergic neurotransmission in the GI tract, as serotonin and acetylcholine are the principal neurotransmitters that stimulate GI motility. 5-HTP is absorbed by enterochromaffin cells in the epithelium, in which it is decarboxylated to serotonin using pyridoxal 5’ phosphate as a cofactor. 5-HTP stimulates enteric neurons through activation of 5HT4 receptors. Ginger modulates serotonin signaling by additional 5HT4 stimulation and by binding type 3 (5HT3) receptors in the enteric nervous system and brain stem, supporting gastric emptying, intestinal transit, healthy visceral sensation and upper GI comfort. Acetyl L-carnitine supports autonomic neuronal health and contributes acetyl groups for the synthesis of acetylcholine, supporting neurotransmission of signals to encourage healthy motility.SUGGESTED USAGEPure Encapsulations recommends 3 capsules, 1-2 times daily, between meals.INGREDIENTSThree vegetable capsules contain:vitamin B6 (as pyridoxal 5' phosphate) (activated B6) 6.7 mg. ginger 1,000 mg. (Zingiber officinale) extract (root) (standardized to contain 5% gingerols) -acetyl-l-carnitine (free-from) 500mg. 5-hydroxytryptophan 50 mgother ingredients: vegetarian capsule (cellulose, water)WARNINGSNot to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use. Do not use concurrently with SSRI medications or MAO inhibitors.Ginger may be contra-indicated with blood thinning medications. Consult your physician for more information.Keep out of reach of children. ADDITIONAL INFORMATIONHypo-allergenic dietary supplement